BDBM50220280 (S)-1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylpiperidin-2-yl)cyclopropyl 4-(2-hydroxyethyl)-2-methylpiperazine-1-carboxylate::CHEMBL392059

SMILES CC[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(Cl)cc1)C1(CC1)OC(=O)N1CCN(CCO)C[C@@H]1C

InChI Key InChIKey=SBTDYVQAJSLKGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220280   

TargetAmyloid-beta precursor protein(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220280((S)-1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylp...)
Affinity DataIC50: 12nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane A-beta-40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220280((S)-1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylp...)
Affinity DataIC50: 14nMAssay Description:Inhibition of gamma-secretase assessed as reduction of cell A-beta-40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed