BDBM50220578 6-(2-(4-(3,4-dihydro-1H-isochromen-7-yl)-4-hydroxypiperidin-1-yl)-1-hydroxypropyl)-3,4-dihydroquinolin-2(1H)-one::CHEMBL246817

SMILES CC(C(O)c1ccc2NC(=O)CCc2c1)N1CCC(O)(CC1)c1ccc2CCOCc2c1

InChI Key InChIKey=XYESQXUVTLGLPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220578   

LigandPNGBDBM50220578(6-(2-(4-(3,4-dihydro-1H-isochromen-7-yl)-4-hydroxy...)
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220578(6-(2-(4-(3,4-dihydro-1H-isochromen-7-yl)-4-hydroxy...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed