BDBM50220582 6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-1-hydroxypropyl)-3-methyl-3,4-dihydroquinazolin-2(1H)-one::CHEMBL246816

SMILES CC(C(O)c1ccc2NC(=O)N(C)Cc2c1)N1CCC(O)(CC1)c1ccc(F)cc1

InChI Key InChIKey=KFKPYSORIJDHRO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220582   

LigandPNGBDBM50220582(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220582(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220582(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed