BDBM50220697 (R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cyclohex-2-enyl)piperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-4-methylpiperazine-2-carboxamide::CHEMBL250719

SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCCC=C1)C(=O)NC(C)(C)C

InChI Key InChIKey=JIITXTWOEYNJJB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220697   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220697((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cyclohex-...)
Affinity DataIC50: 64nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220697((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cyclohex-...)
Affinity DataEC50:  85nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed