BDBM50220702 (R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-tetrazol-5-yl)methyl)-4-(tetrahydro-2H-pyran-4-yl)piperidin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL399715

SMILES Cn1nnnc1CC1(CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCOCC1

InChI Key InChIKey=GQMIABUSQPZJIB-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50220702   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220702((R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-t...)
Affinity DataIC50: 32nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220702((R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-t...)
Affinity DataEC50:  157nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220702((R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-t...)
Affinity DataEC50:  2.95E+3nMAssay Description:Antagonist activity at human MC3R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220702((R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-t...)
Affinity DataEC50:  2.95E+3nMAssay Description:Antagonist activity at human MC5R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed