BDBM50220869 8-chloro-2-(3-(4-phenylpiperidin-1-yl)propyl)quinazolin-4(3H)-one::CHEMBL250489

SMILES Clc1cccc2c1nc(CCCN1CCC(CC1)c1ccccc1)[nH]c2=O

InChI Key InChIKey=ZUWRJCHNQXZPKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220869   

TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220869(8-chloro-2-(3-(4-phenylpiperidin-1-yl)propyl)quina...)
Affinity DataIC50: 103nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50220869(8-chloro-2-(3-(4-phenylpiperidin-1-yl)propyl)quina...)
Affinity DataIC50: 610nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220869(8-chloro-2-(3-(4-phenylpiperidin-1-yl)propyl)quina...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed