BDBM50221800 CHEMBL5275616

SMILES OS(=O)(=O)Nc1ccc(CN(C(=O)c2cccnc2Cl)c2nc(cs2)-c2ccccc2)cc1

InChI Key InChIKey=CJJTVPXKJCZYFM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221800   

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
National Engineering Research Center For The Emergency Strategic Drug

Curated by ChEMBL
LigandPNGBDBM50221800(CHEMBL5275616)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant human PTPbeta using DiFMUP as substrate preincubated for 10 mins followed by substrate addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Engineering Research Center For The Emergency Strategic Drug

Curated by ChEMBL
LigandPNGBDBM50221800(CHEMBL5275616)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of recombinant PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
National Engineering Research Center For The Emergency Strategic Drug

Curated by ChEMBL
LigandPNGBDBM50221800(CHEMBL5275616)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of recombinant SHP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
National Engineering Research Center For The Emergency Strategic Drug

Curated by ChEMBL
LigandPNGBDBM50221800(CHEMBL5275616)
Affinity DataIC50: 3.28E+4nMAssay Description:Inhibition of recombinant TC-PTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
National Engineering Research Center For The Emergency Strategic Drug

Curated by ChEMBL
LigandPNGBDBM50221800(CHEMBL5275616)
Affinity DataIC50: 4.23E+4nMAssay Description:Inhibition of recombinant LAR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed