BDBM50222021 (1R,3aR,4aS,8aS,9S,9aS)-6-(cyclopropylcarbonyl)-decahydro-1-methyl-9-[(e)-2-[5-[3-(trifluoromethyl)phenyl]-2-pyridinyl]-ethenyl]furo[3,4-g]isoquinolin-3(1H)-one::CHEMBL389835

SMILES C[C@H]1OC(=O)[C@@H]2C[C@@H]3CN(CC[C@H]3[C@H](\C=C\c3ccc(cn3)-c3cccc(c3)C(F)(F)F)[C@H]12)C(=O)C1CC1

InChI Key InChIKey=WUNXFRUDUJWGPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222021   

TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50222021((1R,3aR,4aS,8aS,9S,9aS)-6-(cyclopropylcarbonyl)-de...)
Affinity DataIC50: 37.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed