BDBM50222488 (R)-3-amino-4-(2,5-difluorophenyl)-1-(3-ethyl-2-(trifluoromethyl)-6,7-dihydro-3H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one::CHEMBL398492

SMILES CCn1c2CN(CCc2nc1C(F)(F)F)C(=O)C[C@H](N)Cc1cc(F)ccc1F

InChI Key InChIKey=WTPYZVMLKJBWRZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50222488   

TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222488((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-ethyl-2-(t...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222488((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-ethyl-2-(t...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222488((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-ethyl-2-(t...)
Affinity DataIC50: 230nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222488((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-ethyl-2-(t...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed