BDBM50223152 3,3,3-trifluoro-N-[(R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylcarbamoyl)-2-(2-trifluoromethoxy-phenyl)-ethyl]-2-methyl-2-trifluoromethyl-propionamide::CHEMBL251371

SMILES CC(C)N1c2ccccc2CC[C@@H](NC(=O)[C@@H](Cc2ccccc2OC(F)(F)F)NC(=O)C(C)(C(F)(F)F)C(F)(F)F)C1=O

InChI Key InChIKey=TZANNCPHJUBFAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223152   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223152(3,3,3-trifluoro-N-[(R)-1-((R)-1-isopropyl-2-oxo-2,...)
Affinity DataIC50: 203nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed