BDBM50223677 CHEMBL439233::N-(2-(3-methylpiperidin-1-yl)phenyl)-5-nitrofuran-2-carboxamide

SMILES CC1CCCN(C1)c1ccccc1NC(=O)c1ccc(o1)[N+]([O-])=O

InChI Key InChIKey=GAKBUDJFUFUSED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223677   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223677(N-(2-(3-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 380nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223677(N-(2-(3-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed