BDBM50223680 5-cyano-furan-2-carboxylic acid (5-guanidinomethyl-2-piperidin-1-yl-phenyl)-amide::CHEMBL400753

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-c1ccc(-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)c(-[#7]-[#6](=O)-c2ccc(o2)C#N)c1

InChI Key InChIKey=DYOLABOLLFKKLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223680   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223680(5-cyano-furan-2-carboxylic acid (5-guanidinomethyl...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223680(5-cyano-furan-2-carboxylic acid (5-guanidinomethyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed