BDBM50223682 5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide::CHEMBL250156

SMILES CN1CCN(Cc2ccc(N3CCCCC3)c(NC(=O)c3ccc(o3)C#N)c2)CC1

InChI Key InChIKey=CBUPZNJHZPSIBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223682   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223682(5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(p...)
Affinity DataIC50: 80nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223682(5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(p...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed