BDBM50223683 5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carboxamide::CHEMBL428056

SMILES [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1CCCCC1

InChI Key InChIKey=BEEHSUPOPGWGQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223683   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50223683(5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 47nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50223683(5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 53nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50223683(5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 360nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed