BDBM50223685 5-cyano-N-(5-cyano-2-(piperidin-1-yl)phenyl)furan-2-carboxamide::CHEMBL399543

SMILES O=C(Nc1cc(ccc1N1CCCCC1)C#N)c1ccc(o1)C#N

InChI Key InChIKey=LONZWZXDMYLWOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223685   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223685(5-cyano-N-(5-cyano-2-(piperidin-1-yl)phenyl)furan-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223685(5-cyano-N-(5-cyano-2-(piperidin-1-yl)phenyl)furan-...)
Affinity DataIC50: 750nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed