BDBM50224168 1,3-dihydro-isoindole-2-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester::CHEMBL392099

SMILES FC(F)(F)c1ccc(Oc2ccc(OC(=O)N3Cc4ccccc4C3)cc2)nc1

InChI Key InChIKey=PXTJWGNBMUJFGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224168   

TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224168(1,3-dihydro-isoindole-2-carboxylic acid 4-(5-trifl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of butyrylcholine esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224168(1,3-dihydro-isoindole-2-carboxylic acid 4-(5-trifl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224168(1,3-dihydro-isoindole-2-carboxylic acid 4-(5-trifl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of acetylcholine esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed