BDBM50224200 2-(2,4-difluorophenylamino)-5-isopropylthiazol-4(5H)-one::CHEMBL236175

SMILES CC(C)c1sc(Nc2ccc(F)cc2F)nc1O

InChI Key InChIKey=GXMUAXPNCVAXSM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224200   

LigandPNGBDBM50224200(2-(2,4-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  26nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224200(2-(2,4-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed