BDBM50224207 2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-one::CHEMBL392452::CHEMBL393908::CHEMBL396617

SMILES CC(C)c1sc(Nc2ccccc2F)nc1O

InChI Key InChIKey=XHOHMOHZBDGVBQ-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50224207   

LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataKi:  7nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11-beta-HSD1 in presence of 3% HSA by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataKi:  17nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataIC50: 97nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224207(CHEMBL396617 | CHEMBL392452 | CHEMBL393908 | 2-(2-...)
Affinity DataKi:  140nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed