BDBM50224461 (1R,5S)-6-(5-ethynylpyridin-3-yl)-3,6-diazabicyclo[3.2.0]-heptane::CHEMBL239722

SMILES C#Cc1cncc(c1)N1C[C@H]2CNC[C@@H]12

InChI Key InChIKey=CIYRARKCUJBDET-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224461   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Neuroscience Research

Curated by ChEMBL
LigandPNGBDBM50224461((1R,5S)-6-(5-ethynylpyridin-3-yl)-3,6-diazabicyclo...)
Affinity DataEC50:  1.34E+4nMAssay Description:Agonist activity at recombinant human alpha-4-beta-2 nAChR expressed in HEK293 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed