BDBM50224541 2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid::CHEMBL248546

SMILES Cc1nc(sc1CCOc1cc(ccc1OCc1ccccc1)C(O)(C(O)=O)C(F)(F)F)-c1ccc(Cl)cc1

InChI Key InChIKey=IYVFVGMFARXLQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224541   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PTP1B in a cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed