BDBM50224548 2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoic acid::CHEMBL400472

SMILES Cc1nc(sc1CCOc1ccc2n(COCC[Si](C)(C)C)cc(c2c1)C(O)(C(O)=O)C(F)(F)F)-c1ccc(Cl)cc1

InChI Key InChIKey=SNCCLXGFWUSVQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224548   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224548(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed