BDBM50224663 (4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)piperazin-1-yl)((3S,4R)-4-(4-chlorophenyl)-1-(1-isobutylpiperidin-4-yl)pyrrolidin-3-yl)methanone::CHEMBL396660

SMILES CC(C)CN1CCC(CC1)N1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccc(C)cc1[C@@H](N)C(C)C

InChI Key InChIKey=KTWJIKZJTCIIJJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224663   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224663((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224663((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human MC4 receptor expressed in CHO cells assessed as inhibition of alpha-MSH-stimulated of cAMP production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed