BDBM50224933 3-fluoro-5-(1,6-naphthyridin-7-yl)benzonitrile::CHEMBL238390

SMILES Fc1cc(cc(c1)-c1cc2ncccc2cn1)C#N

InChI Key InChIKey=PSQNPPVCWZBHDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224933   

TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224933(3-fluoro-5-(1,6-naphthyridin-7-yl)benzonitrile | C...)
Affinity DataIC50: 1.59E+3nMAssay Description:Antagonist activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed