BDBM50225361 Etisulergine

SMILES [H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@@H](CN2C)NS(=O)(=O)N(CC)CC

InChI Key InChIKey=YHEIHLVIKSTGJE-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50225361   

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory activity against serotonin receptor from whole rat brain using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibitory activity against alpha-1 adrenergic receptor from whole rat brain using [3H]WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 480nMAssay Description:In vitro inhibitory activity against alpha-2 adrenergic receptor from rat brain minus cerebellum using [3H]clonidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory activity against serotonin receptor from rat frontal cortex using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]WB 4101 whole rat brain alpha 1-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 480nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]clonidine (Clon) rat brain minus cerebellum Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone calf caudate (SPC) dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone rat frontal cortex (SPFC) serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]serotonin (5-HT) whole rat brain serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225361(Etisulergine)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]dopamine (DA),calf caudate dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed