BDBM50226639 CHEMBL238240::N-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}ethyl){4-[(nitrooxy)methyl]phenyl}carboxamide

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CCNC(=O)c3ccc(O[N+]([O-])=O)cc3)c2c1

InChI Key InChIKey=QUKICXMMPBNHGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226639   

TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226639(N-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-met...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed