BDBM50226644 2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}-N-[3-(nitrooxy)propyl]acetamide::CHEMBL237400

SMILES COc1cc2c(CC(=O)NCCCO[N+]([O-])=O)c(C)n(C(=O)c3ccc(Cl)cc3)c2cc1Cl

InChI Key InChIKey=YCVNAUDTLXBCJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226644   

TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226644(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226644(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed