BDBM50227549 3-(trifluoromethyl)benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate::CHEMBL254006

SMILES FC(F)(F)c1cccc(COC(=O)c2cccc(=O)[nH]2)c1

InChI Key InChIKey=KHUYGJKVYSCEOH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227549   

Target72 kDa type IV collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227549(3-(trifluoromethyl)benzyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50: 150nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227549(3-(trifluoromethyl)benzyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227549(3-(trifluoromethyl)benzyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50: 150nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227549(3-(trifluoromethyl)benzyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed