BDBM50227583 CHEMBL254838::cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate

SMILES O=C(OC1CCCCC1)c1cccc(=O)[nH]1

InChI Key InChIKey=BYXJDCBFAJLZRZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227583   

TargetInterstitial collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227583(cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227583(cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227583(cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227583(cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed