BDBM50227712 CHEMBL254816::N-hydroxy-2-[4-(2-trifluoromethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-acetamide

SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(-c2ccccc2)c(c1)C(F)(F)F

InChI Key InChIKey=URSVZCYOMZVHJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227712   

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227712(N-hydroxy-2-[4-(2-trifluoromethyl-biphenyl-4-yl)-3...)
Affinity DataIC50: 960nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227712(N-hydroxy-2-[4-(2-trifluoromethyl-biphenyl-4-yl)-3...)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed