BDBM50227734 CHEMBL254817::N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-acetamide

SMILES COc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO

InChI Key InChIKey=AFLLOSXTZXYSAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227734   

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227734(N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227734(N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)...)
Affinity DataIC50: 222nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed