BDBM50227849 CHEMBL402746::CHEMBL537229::N-((1R,2S)-2-(hydroxycarbamoyl)cyclopentyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide

SMILES Cc1cc(COc2ccc(cc2)C(=O)N[C@@H]2CCC[C@@H]2C(=O)NO)c2ccccc2n1

InChI Key InChIKey=OXTQTRNMDRGLGO-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50227849   

LigandPNGBDBM50227849(CHEMBL537229 | CHEMBL402746 | N-((1R,2S)-2-(hydrox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50227849(CHEMBL537229 | CHEMBL402746 | N-((1R,2S)-2-(hydrox...)
Affinity DataIC50: 2nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50227849(CHEMBL537229 | CHEMBL402746 | N-((1R,2S)-2-(hydrox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50227849(CHEMBL537229 | CHEMBL402746 | N-((1R,2S)-2-(hydrox...)
Affinity DataKi: >2.13E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50227849(CHEMBL537229 | CHEMBL402746 | N-((1R,2S)-2-(hydrox...)
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50227849(CHEMBL537229 | CHEMBL402746 | N-((1R,2S)-2-(hydrox...)
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed