BDBM50228414 CHEMBL239747::diphenyl 1-acetamido-2-(4-guanidinophenyl)ethylphosphonate

SMILES [#6]-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=HIAPHZCTQDXMJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228414   

TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228414(diphenyl 1-acetamido-2-(4-guanidinophenyl)ethylpho...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228414(diphenyl 1-acetamido-2-(4-guanidinophenyl)ethylpho...)
Affinity DataIC50: 3.22E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228414(diphenyl 1-acetamido-2-(4-guanidinophenyl)ethylpho...)
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228414(diphenyl 1-acetamido-2-(4-guanidinophenyl)ethylpho...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed