BDBM50228760 (S)-2-((R)-2-(3-chlorophenyl)-2-hydroxyacetamido)-N-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-3-methylbutanamide::(S)-2-[(R)-2-(3-chloro-phenyl)-2-hydroxy-acetylamino]-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-3-methyl-butyramide::CHEMBL403113

SMILES [#6]-[#6](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#8])-c1cccc(Cl)c1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-c1nccs1

InChI Key InChIKey=UGUDQXJLBCAYHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50228760   

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228760((S)-2-((R)-2-(3-chlorophenyl)-2-hydroxyacetamido)-...)
Affinity DataIC50: 116nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228760((S)-2-((R)-2-(3-chlorophenyl)-2-hydroxyacetamido)-...)
Affinity DataIC50: 116nMAssay Description:Binding affinity to human factor 11a assessed as release of p-nitroaniline after 10 to 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228760((S)-2-((R)-2-(3-chlorophenyl)-2-hydroxyacetamido)-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed