BDBM50228767 4''-Hydroxy-Diclofenac::4'-HYDROXY-DICLOFENAC::CHEBI:59613

SMILES OC(=O)Cc1ccccc1Nc1c(Cl)cc(O)cc1Cl

InChI Key InChIKey=KGVXVPRLBMWZLG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228767   

TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50228767(CHEBI:59613 | 4''-Hydroxy-Diclofenac | 4'-HYDROXY-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of [3H]NCS-382 binding to CaMK2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50228767(CHEBI:59613 | 4''-Hydroxy-Diclofenac | 4'-HYDROXY-...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of [3H]NCS-382 binding to CaMK2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50228767(CHEBI:59613 | 4''-Hydroxy-Diclofenac | 4'-HYDROXY-...)
Affinity DataIC50: 7.08E+6nMAssay Description:In vitro inhibition of bovine prostaglandin G/H synthase, using bovine seminal vesicle microsomal preparations; IC50 in umol/LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50228767(CHEBI:59613 | 4''-Hydroxy-Diclofenac | 4'-HYDROXY-...)
Affinity DataIC50: 7.08E+6nMAssay Description:Inhibition of COX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article