BDBM50229571 4-(4-hydroxy-benzylideneamino)-benzenesulfonamide::4-(4-hydroxybenzylideneamino)benzenesulfonamide::CHEMBL270670

SMILES NS(=O)(=O)c1ccc(cc1)\N=C\c1ccc(O)cc1

InChI Key InChIKey=QEZYWFVOEUVTBF-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50229571   

TargetProstaglandin G/H synthase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50229571(4-(4-hydroxy-benzylideneamino)-benzenesulfonamide ...)
Affinity DataIC50: 1.48E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A-23187-stimulated TxB2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50229571(4-(4-hydroxy-benzylideneamino)-benzenesulfonamide ...)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Enscm/Umii/Umr-Cnrs 5635

Curated by ChEMBL
LigandPNGBDBM50229571(4-(4-hydroxy-benzylideneamino)-benzenesulfonamide ...)
Affinity DataKi:  11nMAssay Description:Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Enscm/Umii/Umr-Cnrs 5635

Curated by ChEMBL
LigandPNGBDBM50229571(4-(4-hydroxy-benzylideneamino)-benzenesulfonamide ...)
Affinity DataKi:  80nMAssay Description:Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Enscm/Umii/Umr-Cnrs 5635

Curated by ChEMBL
LigandPNGBDBM50229571(4-(4-hydroxy-benzylideneamino)-benzenesulfonamide ...)
Affinity DataKi:  702nMAssay Description:Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed