BDBM50229663 (S)-tetrahydrofuran-3-yl 4-((4-(4-cyano-2-methylphenyl)-5,6-dihydropyridin-1(2H)-ylsulfonyl)methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate::CHEMBL251830

SMILES Cc1cc(ccc1C1=CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)O[C@H]1CCOC1)C(=O)NO)C#N

InChI Key InChIKey=XWALZJCMHMIYFN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50229663   

LigandPNGBDBM50229663((S)-tetrahydrofuran-3-yl 4-((4-(4-cyano-2-methylph...)
Affinity DataIC50: 107nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50229663((S)-tetrahydrofuran-3-yl 4-((4-(4-cyano-2-methylph...)
Affinity DataIC50: 45nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229663((S)-tetrahydrofuran-3-yl 4-((4-(4-cyano-2-methylph...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed