BDBM50229729 CHEMBL4097555

SMILES COc1cc(cc(OC)c1OC)C1CC(=NN1C(C)=O)c1ccc(Nc2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1

InChI Key InChIKey=HWCHQLGZTBGQFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229729   

TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229729(CHEMBL4097555)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229729(CHEMBL4097555)
Affinity DataIC50: 8.61E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed