BDBM50230186 CHEMBL4104466

SMILES Nc1ncc2ccc(cc2n1)-c1ccc(NC(=S)Nc2ccc(Cl)cc2Cl)cc1

InChI Key InChIKey=JXZUQLGBYDHSAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230186   

TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230186(CHEMBL4104466)
Affinity DataIC50: 164nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230186(CHEMBL4104466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2019
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230186(CHEMBL4104466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2019
Entry Details Article
PubMed