BDBM50230317 CHEMBL4091022

SMILES CSc1nc(NCc2ccccc2)c2ccn(Cc3ccc(F)cc3)c2n1

InChI Key InChIKey=RENHBYHXMSFCBW-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50230317   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50230317(CHEMBL4091022)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged Src expressed in Sf21 cells using KVEKIGEGTYGVVYK as substrate after 10 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50230317(CHEMBL4091022)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged Fyn expressed in baculovirus infected Sf21 cells using KVEKIGEGTYGVVYK as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50230317(CHEMBL4091022)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Flt3 (unknown origin) using KVEKIGEGTYGVVYK as substrate after 10 mins in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50230317(CHEMBL4091022)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed