BDBM50230355 CHEMBL4061884

SMILES OCCNC(=O)COc1cc2[nH]c(cc2cc1Cl)C(=O)N[C@H](CO)c1ccc(cc1)C(O)=O

InChI Key InChIKey=XGDHHSGGMJZWOE-UHFFFAOYSA-N

Data  1 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50230355   

TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PHGDH (unknown origin) by FLINT methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed