BDBM50230979 CHEMBL4098962

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(Cn4cccc4CN4CCN(C)CC4)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=VJIHUUUCSYAGEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230979   

TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230979(CHEMBL4098962)
Affinity DataIC50: 165nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230979(CHEMBL4098962)
Affinity DataIC50: 68nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed