BDBM50231775 (R)-5-(4-chlorophenyl)-N-(1-(4-(3-(4-(cyclopropanecarbonyl)phenoxy)propyl)piperazin-1-yl)-1-oxopropan-2-yl)furan-2-carboxamide::CHEMBL251241

SMILES C[C@@H](NC(=O)c1ccc(o1)-c1ccc(Cl)cc1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1

InChI Key InChIKey=CKOAURGENMZQGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231775   

TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231775((R)-5-(4-chlorophenyl)-N-(1-(4-(3-(4-(cyclopropane...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant Nav1.8 channel expressed in HEK293 cells by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231775((R)-5-(4-chlorophenyl)-N-(1-(4-(3-(4-(cyclopropane...)
Affinity DataIC50: 800nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by isotope efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed