BDBM50232326 CHEMBL4102214

SMILES c1ccc(C(c2ccccc2)c2nnc(Cc3nc4ccccc4[nH]3)o2)cc1

InChI Key InChIKey=OSHRLMBZRPMAQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232326   

TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232326BDBM50232326(CHEMBL4102214)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232326BDBM50232326(CHEMBL4102214)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232326BDBM50232326(CHEMBL4102214)
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed