BDBM50232330 CHEMBL4068254

SMILES c1ccc(-c2nnc(Cc3nc4ccccc4[nH]3)o2)cc1

InChI Key InChIKey=HDKMMBRKVCIVNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232330   

TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232330BDBM50232330(CHEMBL4068254)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232330BDBM50232330(CHEMBL4068254)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232330BDBM50232330(CHEMBL4068254)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed