BDBM50232344 CHEMBL4066118

SMILES c1ccc2c(Cc3nnc(Cc4nc5ccccc5[nH]4)o3)cccc2c1

InChI Key InChIKey=QTILXTTYIGTLDB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232344   

TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232344BDBM50232344(CHEMBL4066118)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232344BDBM50232344(CHEMBL4066118)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232344BDBM50232344(CHEMBL4066118)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed