BDBM50233450 CHEMBL4073826

SMILES COc1cc(OC)c(Cl)c(COc2cnc(Nc3c(Cl)cccc3NC(=O)C=C)nc2)c1Cl

InChI Key InChIKey=PJQQHDMMDOTPEL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233450   

TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233450(CHEMBL4073826)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR4 (781 to 1338 residues) expressed in baculovirus expression system using Tyr 4 peptide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233450(CHEMBL4073826)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR3 (399 to 806 residues) expressed in baculovirus expression system using Tyr 4 peptide as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233450(CHEMBL4073826)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR1 (308 to 731 residues) expressed in baculovirus expression system using Tyr 4 peptide as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233450(CHEMBL4073826)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR2 (403 to 822 residues) expressed in baculovirus expression system using Tyr 4 peptide as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2019
Entry Details Article
PubMed