BDBM50233471 (2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamine::1-(2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamine::CHEMBL257423

SMILES CN(C)Cc1ccccc1Oc1ccc(Cl)cc1

InChI Key InChIKey=WYCWVUGQDBCHEF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50233471   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 1.68nMAssay Description:Inhibition of serotonin reuptake at SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 1.98E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]5HT uptake at human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 124nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 256nMAssay Description:Inhibition of [3H]NA uptake at human NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed