BDBM50233472 (2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamine::CHEMBL257424

SMILES CN(C)Cc1ccccc1Oc1cccc(Cl)c1

InChI Key InChIKey=BSYKAWMTFFQDNB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50233472   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233472((2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 910nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50233472((2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233472((2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233472((2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 238nMAssay Description:Inhibition of [3H]5HT uptake at human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50233472((2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 82nMAssay Description:Inhibition of [3H]NA uptake at human NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233472((2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50: 194nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed