BDBM50233600 CHEMBL4098428::US10882838, Example 1.10

SMILES [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)C(=O)OCCCn1ccnc1

InChI Key InChIKey=WJRVVIKOSPKUCK-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50233600   

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataEC50:  1nMAssay Description:Agonist activity at CB1 receptor in rat brain membranes assessed as reduction in forskolin-stimulated cAMP level measured from 3 data points after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Northeastern University

US Patent
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataKi:  1.20nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Northeastern University

US Patent
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
Northeastern University

US Patent
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataKi:  2nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent

TargetCannabinoid receptor 2(Mouse)
Northeastern University

US Patent
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataKi:  3.40nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233600(CHEMBL4098428 | US10882838, Example 1.10)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed