BDBM50233616 CHEMBL4071457::US10882838, Example 1.27

SMILES [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(CC(=O)OCCCCBr)cc(O)c21

InChI Key InChIKey=CDXTXOOFOAEXDG-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50233616   

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233616(CHEMBL4071457 | US10882838, Example 1.27)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233616(CHEMBL4071457 | US10882838, Example 1.27)
Affinity DataKi:  2.20nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Northeastern University

US Patent
LigandPNGBDBM50233616(CHEMBL4071457 | US10882838, Example 1.27)
Affinity DataKi:  7.10nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Northeastern University

US Patent
LigandPNGBDBM50233616(CHEMBL4071457 | US10882838, Example 1.27)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
Northeastern University

US Patent
LigandPNGBDBM50233616(CHEMBL4071457 | US10882838, Example 1.27)
Affinity DataKi:  11.6nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent

TargetCannabinoid receptor 2(Mouse)
Northeastern University

US Patent
LigandPNGBDBM50233616(CHEMBL4071457 | US10882838, Example 1.27)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed